Protein Domains & Interactions

This lecture covers the mediation of protein interactions by domains, scaffolds, and local concentrations. It delves into the early days of biochemistry, metabolic pathways, cellular signaling, and biological networks. The lecture also explores the molecular organization of cellular signaling and the regulation of protein activity through domains. Additionally, it discusses the combination of domains with different functions, the concept of effective molarity, and the role of scaffolds in regulating and integrating proteins. The presentation concludes with an overview of protein-protein interaction networks and genome-wide approaches to studying protein interactions.