This lecture covers the fundamental nature of computer science and engineering, emphasizing the challenges and opportunities in the field. It discusses the importance of undergraduate education in computing, the role of computer science in addressing societal needs such as sustainability and welfare, and the impact of electronic devices on various application areas. The lecture also explores smart energy production, data centers, body monitoring technologies, environmental monitoring, and novel electronic devices. It highlights the interdisciplinary nature of electronic engineering and the need for a systems view of electronic devices to drive technological advancements.