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This lecture covers the fundamentals of mechanical construction, focusing on mechanical systems composed of multiple mobile sub-assemblies and mechanical connections between them. Topics include blocking degrees of freedom through clamping or obstacles, standardized mechanical connections, bolted assemblies, thread functions, and securing bolted joints against loosening. The instructor emphasizes the importance of proper design rules for bolted assemblies, the architecture of bolting, types of bolts, securing techniques, and the resistance of bolts. Practical exercises and normative references are also discussed.