Mitochondrial Dynamics: Hsp70 and MBP Folding

This lecture explores the dynamics of the mitochondrial Hsp70 (Ssc1) and the folding of the maltose binding protein (MBP) from a single molecule perspective. It covers topics such as Förster Resonance Energy Transfer, sensitivity adjustments, and the conformational cycle of Ssc1. The instructor delves into the interaction between Hsp70 and cochaperones, the folding and unfolding processes, and the regulation of different functions. Additionally, the lecture discusses the use of single-molecule FRET solution experiments to study the dynamics of these proteins.