This lecture covers the historical timeline of neural interfaces, from ancient Egypt to modern-day advancements like brain-computer interfaces and deep brain stimulation. It delves into the components of a neural interface, including recording, stimulation, transducers, and data processing. The lecture also explores key concepts related to the skeletal, nervous, circulatory, digestive, and respiratory systems, as well as medtech technologies like prosthetic hands, pacemakers, and deep brain stimulators.