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Explores cancer therapies, including chemotherapies and targeted therapies, discussing mechanisms of action, limitations, and the development of resistance.
Explores DNA repair mechanisms, including BER, MMR, NER, and repair of double-strand breaks, as well as the impact of UV-induced lesions and resistance to PARP inhibitors.
Delves into pioneer transcription factors, chromatin organization, and cell fate transitions, showcasing examples of reprogramming and discussing the potential applications in regenerative medicine.
