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This lecture covers the proper use of an analytical balance to weigh approximately 500 mg of copper sulfate. The instructor demonstrates the importance of a clean and level balance, as well as factors to consider during weighing, such as avoiding magnetic fields and ensuring the product is at room temperature. The process of weighing, including using a container, adding the product gradually, and handling different types of substances, is detailed. The lecture emphasizes the need for cleanliness, proper handling techniques, and post-weighing procedures to maintain the accuracy of measurements.