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This lecture covers the stability of metal complexes and the calculation of formation constants for different ligands. It discusses the Irving-Williams series, stepwise formation constants for aluminum complexes with fluoride and oxalate, and the Gibbs energy change for specific reactions. The instructor explains the reasons behind the number of stepwise constants for each ligand and the driving force for complex formation. Additionally, the lecture explores the impact of different reactants on breaking specific complexes, highlighting the importance of binding energy in complex stability.