This lecture covers the impact of non-idealities in operational amplifiers (OPAMPs) on amplifier circuits. It discusses the effect of finite gain-bandwidth product on both noninverting and inverting amplifiers, including frequency-dependent gain. The lecture also delves into slew-rate limitations, settling time analysis, power supply rejection ratio (PSRR), and common mode rejection ratio (CMRR. It further explores the selection of proper OPAMPs, SPICE macro-models, and instrumentation amplifiers. The content extends to the design of transresistance amplifiers, photodetector amplifiers, and operational transconductance amplifiers (OTAs).