This lecture covers the relationship between materials' chemistry and their properties, focusing on ductility, hardness, and toughness in metals, polymers, and ceramics. It explains concepts like ductile rupture, stress intensity factor, and tenacity, as well as the role of dislocations in plastic deformation and energy storage. The lecture also discusses the hardening mechanisms in materials, such as solid solution hardening, work hardening, and precipitation hardening. It explores how grain boundaries and dislocation movements affect the strength of materials, and the different stages of tensile deformation in metals. Additionally, it delves into the behavior of polymers in different temperature ranges and strain rates.