Publications by Jean-Jacques Meister

Intercellular Ultrafast Calcium Wave Velocity and Propagation of Spontaneous Electrical Activity in A7r5 Cells at Physiological Temperature

Jean-Jacques Meister, Jairo Camilo Quijano Perez

Cell Press2018

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Jean-Jacques Meister, Chiara Gabella, Alexander Verkhovskiy, Franck Claude Raynaud, Alicia Carine Bornert, Mark Etienne Ambühl

How cells break symmetry and organize activity at their edges to move directionally is a fundamental question in cell biology. Physical models of cell motility commonly incorporate gradients of regulatory proteins and/or feedback from the motion itself to ...

Nature Publishing Group2016

Intercellular ultrafast Ca2+ wave in vascular smooth muscle cells: numerical and experimental study

Jean-Jacques Meister, Niccolo Piacentini, Franck Claude Raynaud, Jairo Camilo Quijano Perez

Vascular smooth muscle cells exhibit intercellular Ca2+ waves in response to local mechanical or KCl stimulation. Recently, a new type of intercellular Ca2+ wave was observed in vitro in a linear arrangement of smooth muscle cells. The intercellular wave w ...

Nature Research2016

Microsurgery-aided in-situ force probing reveals extensibility and viscoelastic properties of individual stress fibers

Jean-Jacques Meister, Chiara Gabella, Alexander Verkhovskiy, Benoît Vianay, Céline Jeanne Labouesse

Actin-myosin filament bundles (stress fibers) are critical for tension generation and cell shape, but their mechanical properties are difficult to access. Here we propose a novel approach to probe individual peripheral stress fibers in living cells through ...

Nature Research2016

Cell Shape Dynamics Reveal Balance of Elasticity and Contractility in Peripheral Arcs

Jean-Jacques Meister, Chiara Gabella, Alexander Verkhovskiy, Benoît Vianay, Céline Jeanne Labouesse

The mechanical interaction between adherent cells and their substrate relies on the formation of adhesion sites and on the stabilization of contractile acto-myosin bundles, or stress fibers. The shape of the cell and the orientation of these fibers can be ...

Cell Press2015

Evaluating Tension in Actomyosin Bundles at the Cell Periphery

Jean-Jacques Meister, Niccolo Piacentini, Benoît Vianay, Céline Jeanne Labouesse

Cell Press2014

Ultra-soft cantilevers and 3-D micro-patterned substrates for contractile bundle tension measurement in living cells

Jean-Jacques Meister, Niccolo Piacentini, Chiara Gabella, Alexander Verkhovskiy, Benoît Vianay

Actin-myosin microfilament bundles or stress-fibers are the principal tension-generating structures in the cell. Their mechanical properties are critical for cell shape, motion, and interaction with other cells and extracellular matrix, but were so far dif ...

Royal Society of Chemistry2014

Contact Angle at the Leading Edge Controls Cell Protrusion Rate

László Forró, Jean-Jacques Meister, Niccolo Piacentini, Chiara Gabella, Alexander Verkhovskiy, Sylvia Jeney, Elena Bertseva, Alicia Carine Bornert

Plasma membrane tension and the pressure generated by actin polymerization are two antagonistic forces believed to define the protrusion rate at the leading edge of migrating cells [1-5]. Quantitatively, resistance to actin protrusion is a product of membr ...

Elsevier2014

Ultrafast Calcium Wave in Cultured Vascular Smooth Muscle Cells

Jean-Jacques Meister, Jairo Camilo Quijano Perez

Cell Press2014

Actin Bundle Stabilization During Cell Spreading on Micropatterned Substrates

Jean-Jacques Meister, Benoît Vianay, Josiane Angèle Charlotte Smith-Clerc

Cell Press2014