Publications by Stephan Morgenthaler

Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression

Background Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. CRC deaths can be reduced with prevention and early diagnosis. Circulating tumor DNA-based liquid biopsies, are emerging tools for cancer detection. However, ...

2024

Innovative Biomarkers for Obesity and Type 1 Diabetes Based on Bifidobacterium and Metabolomic Profiling

Stephan Morgenthaler, Paul Refinetti, Mariya Yuryevna Skvortsova

The role of Bifidobacterium species and microbial metabolites such as short-chain fatty acids (SCFAs) and human milk oligosaccharides in controlling intestinal inflammation and the pathogenesis of obesity and type 1 diabetes (T1D) has been largely studied ...

MDPI2024

Gaia Focused Product Release: A catalogue of sources around quasars to search for strongly lensed quasars

Stephan Morgenthaler, Richard Irving Anderson

All rights reserved.Context. Strongly lensed quasars are fundamental sources for cosmology. The Gaia space mission covers the entire sky with the unprecedented resolution of 0.18âÃ Â€ ³ in the optical, making it an ideal instrument to search for gravitatio ...

2024

Gaia Focused Product Release: Radial velocity time series of long-period variables

Stephan Morgenthaler, Shuangqing Liao

Context. The third Gaia Data Release (DR3) provided photometric time series of more than 2 million long-period variable (LPV) candidates. Anticipating the publication of full radial-velocity data planned with Data Release 4, this Focused Product Release (F ...

Edp Sciences S A2023

Gaia Focused Product Release: Asteroid orbital solution: Properties and assessment

Stephan Morgenthaler, Shuangqing Liao

Context. We report the exploitation of a sample of Solar System observations based on data from the third Gaia Data Release (Gaia DR3) of nearly 157 000 asteroids. It extends the epoch astrometric solution over the time coverage planned for the Gaia DR4, w ...

Edp Sciences S A2023

Gaia Focused Product Release: Sources from Service Interface Function image analysis Half a million new sources in omega Centauri

Stephan Morgenthaler, Shuangqing Liao

Context.Gaia's readout window strategy is challenged by very dense fields in the sky. Therefore, in addition to standard Gaia observations, full Sky Mapper (SM) images were recorded for nine selected regions in the sky. A new software pipeline exploits the ...

Edp Sciences S A2023

Gaia Focused Product Release: Spatial distribution of two diffuse interstellar bands

Stephan Morgenthaler, Shuangqing Liao

Diffuse interstellar bands (DIBs) are absorption features seen in optical and infrared spectra of stars and extragalactic objects that are probably caused by large and complex molecules in the galactic interstellar medium (ISM). Here we investigate the Gal ...

Edp Sciences S A2023

A comprehensive error rate for multiple testing

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Stephan Morgenthaler, Djalel Eddine Meskaldji

Over the last two decades, a large variety of type I error rates and control procedures have been proposed in the field of multiple hypotheses testing. This paper proposes a framework that includes many existing proposals by investigating procedures in whi ...

SPRINGER2020

Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations

Stephan Morgenthaler, Paul Refinetti, Per Olaf Ekstrom

Background ...

FRONTIERS MEDIA SA2020

Identifying gene function and module connections by the integration of multispecies expression compendia

Johan Auwerx, Kristina Schoonjans, Stephan Morgenthaler, Fabrice David, Hao Li, Maroun Bou Sleiman, Elena Katsyuba, Wen Gao, Daria Rukina, Qingyao Huang

The functions of many eukaryotic genes are still poorly understood. Here, we developed and validated a new method, termed GeneBridge, which is based on two linked approaches to impute gene function and bridge genes with biological processes. First, Gene-Mo ...

Cold Spring Harbor Laboratory2019