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Florian Jousset

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Related publications (13)

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Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...

Wiley-Blackwell2014

Kinetics of Atrial Repolarization Alternans in a Free-Behaving Ovine Model

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Kinetics of Atrial Repolarization Alternans. Introduction: Repolarization alternans (Re-ALT), a beat-to-beat alternation in action potential repolarization, promotes dispersion of repolarization, wavebreaks, and reentry. Recently, Re-ALT has been shown to ...

Wiley-Blackwell2012

Interdisciplinary collaboration between physicians and engineers is now widespread in fundamental and clinical studies, due to the increasing complexity of the physiological problems tackled, and the development of novel measurement devices and data analys ...

EPFL2011

Long-term intermittent atrial tachycardia decreases activation recovery interval, flattens its kinetics and blunts its rate dependence before sustained atrial fibrillation

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Introduction: We recently observed in an acute ovine model of pacing-induced atrial tachycardia (PIAT) that rapid atrial capture and fibrillatory conduction were prevented by 2:1 capture mediated by decreased excitability. We hypothesize that long-term int ...

2010

Decreased Excitability as a Protective Mechanism Against Repolarization Alternans-Induced Atrial Reentry

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Introduction: We recently observed in human left atrium periods of intermittent 2:1 and 1:1 atrial capture, preceded by atrial repolarization alternans (Re-ALT) during rapid pacing. It remains undetermined whether Re- ALT plays a role in preventing 1:1 atr ...

2010

Rate-dependence of 2:1 atrial capture as a protective mechanism against atrial tachycardia-induced atrial fibrillation

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

We recently observed periods of intermittent 2:1 atrial capture in the human left atrium (LA), preceded by atrial repolarization alternans during pacing-induced atrial tachycardia (PIAT). The mechanism involved in resumption of 1:1 atrial capture remains u ...

2010

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Introduction: It has been shown that repolarization alternans (Re-ALT), a beat-to-beat alternation in action potential duration, enhances dispersion of repolarization DOR above a critical heart rate and promotes susceptibility to ventricular arrhythmias. I ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2009

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In pacing-induced models of atrial fibrillation (AF) that mimic atrial high-frequency foci, the increase in AF susceptibility over time is not paralleled by any increase in dispersion of repolarization (DOR). Measurements of effective refractory periods (E ...

2009

Predicting Acute Hypotensive Episodes

Jean-Marc Vesin, Mathieu Lemay, Florian Jousset

The goal of the challenge 2009 is to predict which patients will experience acute hypotensive episode (AHE) within a forecast window. AHE may result in dangerous complications and even death. Predicting the onset of AHE would be of clear benefit to a patie ...

2009

Computers in Cardiology / Physionet Challenge 2009: Predicting Acute Hypotensive Episodes

Jean-Marc Vesin, Mathieu Lemay, Florian Jousset

The goal of the Computers in Cardiology / Physionet Challenge 2009 is to predict which patients will experience acute hypotensive episode within a forecast window of one hour. In our study, statistically robust features extracted from the supplied training ...

2009