Publications by Alain Destexhe

Experimental and Computational Study on Motor Control and Recovery After Stroke: Toward a Constructive Loop Between Experimental and Virtual Embodied Neuroscience

Auke Ijspeert, Silvestro Micera, Shravan Tata Ramalingasetty, Marc-Oliver Gewaltig, Emanuele Formento, Maria Pasquini, Egidio Falotico, Lorenzo Vannucci, Axel von Arnim, Emmanouil Angelidis

Being able to replicate real experiments with computational simulations is a unique opportunity to refine and validate models with experimental data and redesign the experiments based on simulations. However, since it is technically demanding to model all ...

FRONTIERS MEDIA SA2020

The Scientific Case for Brain Simulations

Felix Schürmann, Michele Migliore, Alain Destexhe

A key element of the European Union's Human Brain Project (HBP) and other large-scale brain research projects is the simulation of large-scale model networks of neurons. Here, we argue why such simulations will likely be indispensable for bridging the scal ...

CELL PRESS2019

A comprehensive workflow for general-purpose neural modeling with highly configurable neuromorphic hardware systems

Eilif Benjamin Muller, Alain Destexhe, Marc-Olivier Schwartz

In this article, we present a methodological framework that meets novel requirements emerging from upcoming types of accelerated and highly configurable neuromorphic hardware systems. We describe in detail a device with 45 million programmable and dynamic ...

2011

Minimal Hodgkin-Huxley type models for different classes of cortical and thalamic neurons

Henry Markram, Alain Destexhe

We review here the development of Hodgkin-Huxley (HH) type models of cerebral cortex and thalamic neurons for network simulations. The intrinsic electrophysiological properties of cortical neurons were analyzed from several preparations, and we selected th ...

2008