Publications by Sandrine Gerber

Surface Functionalization of Nanocarriers with Anti-EGFR Ligands for Cancer Active Targeting

Active cancer targeting consists of the selective recognition of overexpressed biomarkers on cancer cell surfaces or within the tumor microenvironment, enabled by ligands conjugated to drug carriers. Nanoparticle (NP)-based systems are highly relevant for ...

MDPI2025

DNA Encapsulation in Polymeric-Based Nanomaterials for Authentication and Tracking

Sandrine Gerber, François Rémi Pierre Noverraz

Fuel theft poses a significant threat to economic stability, undermining governments revenues and global security while benefiting criminal networks. Combating this issue requires coordinated efforts including innovative technological solutions to secure t ...

American Chemical Society (ACS)2025

Emergence of highly coherent two-level systems in a noisy and dense quantum network

Sandrine Gerber, Gabriel Aeppli

Quantum sensors and qubits are usually two-level systems (TLS), the quantum analogues of classical bits assuming binary values 0 or 1. They are useful to the extent to which superpositions of 0 and 1 persist despite a noisy environment. The standard prescr ...

Nature Portfolio2024

Recent Advances in Alginate-Based Hydrogels for Cell Transplantation Applications

Sandrine Gerber, François Rémi Pierre Noverraz, Alireza Kavand

With its exceptional biocompatibility, alginate emerged as a highly promising biomaterial for a large range of applications in regenerative medicine. Whether in the form of microparticles, injectable hydrogels, rigid scaffolds, or bioinks, alginate provide ...

2024

FAP Targeting of Photosensitizer-Loaded Polymersomes for Increased Light-Activated Cell Killing

Sandrine Gerber

As current chemo- and photodynamic cancer therapies are associated with severe side effects due to a lack of specificity and to systemic toxicity, innovative solutions in terms of targeting and controlled functionality are in high demand. Here, we present ...

American Chemical Society2024

“Grafting-from” and “Grafting-to” Poly(N-isopropyl acrylamide) Functionalization of Glass for DNA Biosensors with Improved Properties

Sandrine Gerber, Mounir Driss Mensi, Alireza Kavand, Pauline Skigin, Perrine Agnes Edith Robin

Surface-based biosensors have proven to be of particular interest in the monitoring of human pathogens by means of their distinct nucleic acid sequences. Genosensors rely on targeted gene/DNA probe hybridization at the surface of a physical transducer and ...

MDPI AG2024

Modulating the Surface Properties of Lithium Niobate Nanoparticles by Multifunctional Coatings Using Water-in-Oil Microemulsions

Sandrine Gerber, Alessandra Spada, Adrian Stefan Gheata, Manon Inès Noëlla Wittwer

Inorganic nanoparticles (NPs) have emerged as promising tools in biomedical applications, owing to their inherent physicochemical properties and their ease of functionalization. In all potential applications, the surface functionalization strategy is a key ...

2023

Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry

Sandrine Gerber, Alireza Kavand, Mounir Driss Mensi, Lucas Mayoraz, Perrine Agnes Edith Robin

The COVID-19 pandemic has highlighted the necessity to develop fast, highly sensitive and selective virus detection methods. Surface-based DNA-biosensors are interesting candidates for this purpose. Functionalization of solid substrates with DNA must be pr ...

2023

Nonclassical Nucleation and Crystallization of LiNbO3 Nanoparticles from the Aqueous Solvothermal Alkoxide Route

Sandrine Gerber, Aurélien Bornet, Adrian Stefan Gheata

The exact molecular reaction pathway and crystallization mechanisms of LiNbO3 nanoparticles under solvothermal conditions are derived through extensive time- and temperature-resolved experiments allowing to track all the transient molecular and solid speci ...

Wiley-V C H Verlag Gmbh2023

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

Sandrine Gerber, Mounir Driss Mensi, Pauline Skigin, Perrine Agnes Edith Robin, Lucas Mayoraz

DNA biosensors are promising candidates for the development of point-of-care diagnosis methods. They can be inserted in microfluidic platforms, are often non-expensive, and can be produced for a variety of targeted analytes. However, their development face ...

Wiley-VHCA AG2023