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Sylvain Favre

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Related publications (9)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Synthetic studies toward the CD spiroketal of spongistatins

Pierre Vogel, Sandrine Gerber, Sylvain Favre

Starting from the readily available meso-methylenedi(8-oxa-3-oxobicyclo[3.2.1]hept-6-en-1-yl) (1), meso-1,1'-methylidene [(4R,4'S,6R,6'S)-4,6-dioxycyclohept-1-en-1-yl]tetrasilylethers (7, 8) were obtained and transformed into all-syn 1,3,5,11,13,15-hexahyd ...

Wiley-Blackwell2010

Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors

Pierre Vogel, Sylvain Favre

Four branched tetra- and pentahydroxylated azepanes have been synthesized from a common azepane precursor through dihydroxylation followed by deoxygenation. They have been assayed as glycosidase inhibitors on a panel of 22 glycosidases and one methylated a ...

2012

New efficient synthetic strategies towards the AB and CD spiroketal fragments of spongistatins and analogues

For thousands of years, nature provided us remedies to treat diseases and its biologically active molecules inspired chemists for the development of new drugs. In 1993, three research groups independently reported the isolation, from sponges, of spongistat ...

EPFL2009