Publications by Lydiane Jeanine Saucède

Comparison of methods to achieve robust design decisions for hydropower projects: A case study

Anton Schleiss, Lydiane Jeanine Saucède, Felix Oberrauch

Hydropower&Dams, Aqua Media International2019

Switch-peptides: from conformational studies to Alzheimer's disease

Hilal Lashuel, Karine Murat, Richard Alan Mimna, Jacques Dubochet, Lydiane Jeanine Saucède, Sonia Dos Santos, Marie-Stéphanie Camus, Jérémy Bérard

A review. Studies on designed peptides that exhibit high tendencies for medium-induced conformational transitions have recently attracted much attention because structural changes are considered as mol. key processes in degenerative diseases. The exptl. ac ...

2006

Switch-peptides as folding precursors in amyloid fibrillogenesis

Sonia Dos Santos, Richard Alan Mimna, Karine Murat, Lydiane Jeanine Saucède, Marie-Stéphanie Camus, Jérémy Bérard

Intramol. O,N-acyl migration reactions were used as structural switch (S-elements) from a depsipeptide bond contg., unfolded state (Soff) to an all-amide, native states (Son). Chem. or enzymically triggered acyl migrations allowed for the controlled induct ...

2006

"Switch peptides" : conception et synthèse d'inhibiteurs ou destructeurs potentiels de fibrilles amyloïdes

Lydiane Jeanine Saucède

Despite of considerable progress in the research at the interface of Chemistry, Biology and Medicine, neurodegenerative diseases affect more and more seriously our ageing population and remain a real therapeutic challenge for researcher. Nevertheless, adva ...

EPFL2006

Switch on amyloid beta peptide self-assembly by enzyme-triggered acyl migration

Sonia Dos Santos, Richard Alan Mimna, Karine Murat, Lydiane Jeanine Saucède, Marie-Stéphanie Camus

2005

Switch-peptides: Controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations

Sonia Dos Santos, Richard Alan Mimna, Karine Murat, Lydiane Jeanine Saucède

2005