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Whole-cell patch-clamp recordings followed by histochemical staining and single-cell RT-PCR were obtained from 180 Martinotti interneurones located in layers II to VI of the somatosensory cortex of Wistar rats (P13-P16) in order to examine their anatomical ...
It is well established that sensory stimulation results in the activity of multiple functional columns in the neocortex. The manner in which neurones within each column are active in relation to each other is, however, not known. Multiple whole-cell record ...
The structure of cross-correlations between subthreshold potentials of neocortical neurons was recently examined. Characteristic features included broad widths and significant peak advances. It was suggested that dynamic synapses shape these cross-correlat ...
The functions performed by different neural microcircuits depend on the anatomical and physiological properties of the various synaptic pathways connecting neurons. Neural microcircuits across various species and brain regions are similar in terms of their ...
2005
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Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions that are supported by the neocortex. The neocortex, which forms almost 80% of the human brain, seems to have arisen from repeated duplication of a stereotypical micr ...
2004
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A model is presented that allows prediction of the probability for the formation of appositions between the axons and dendrites of any two neurons based only on their morphological statistics and relative separation. Statistics of axonal and dendritic morp ...
2003
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A central debate regarding neocortical function concerns the degree to which the underlying microcircuitry is stereotypically organized. Stereotypy reflects invariance in structure and function, as a result of common genetic templates and environmental con ...
2002
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Information processing in neocortex can be very fast, indicating that neuronal ensembles faithfully transmit rapidly changing signals to each other. Apart from signal-to-noise issues, population codes are fundamentally constrained by the neuronal dynamics. ...
2004
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To understand the interface between global brain function and molecular neuroscience--that is, the microcircuit level--a major challenge. Such understanding is prerequisite if we are to account for neural function in cellular terms. Very few vertebrate mic ...