Publications by Luc Blecha | EPFL Graph Search

Mechanical interaction between cells and fluid for bone tissue engineering scaffold: modulation of the interfacial shear stress

Dominique Pioletti, Alexandre Terrier, Lalaonirina Rakotomanana Ravelonarivo, Luc Blecha

An analytical model of the fluid/cell mechanical interaction was developed. The interfacial shear stress, due to the coupling between the fluid and the cell deformation, was characterized by a new dimensionless number . For above a critical value, the flui ...

2010

Targeted mechanical properties for optimal fluid motion inside artificial bone substitutes

Dominique Pioletti, Alexandre Terrier, Lalaonirina Rakotomanana Ravelonarivo, Luc Blecha

The goal of this study was to develop a method that identifies optimal elastic modulus, Poisson’s ratio, porosity and permeability values for mechanically stressed bone substitute. It was hypothesized that porous bone substitute that favors the transport o ...

2009

Theroretical and experimental multi-scale study of an artificial bone construct : from tibial osteotomy to cell/fluid interaction

Luc Blecha

Synthetic bone substitutes are potentially the future gold standard in orthopaedic and traumatologic surgery. The availability of these bone substitutes with different biomechanical properties may well replace autografts in the future as they overcome comp ...

EPFL2007

Mechanical Interaction Between Fluid And Cell Modulates Fluid Flow Induced Shear Stress

Dominique Pioletti, Lalaonirina Rakotomanana Ravelonarivo, Luc Blecha

2006

How plate positioning impacts the biomechanics of the open wedge tibial osteotomy; a finite element analysis

Dominique Pioletti, Pierre-Etienne Bourban, Luc Blecha

A numerical model of the medial open wedge tibial osteotomy based on the finite element method was developed. Two plate positions were tested numerically. In a configuration, (a), the plate was fixed in a medial position and (b) in an anteromedial position ...

2005