Person
Gérald Coste
This person is no longer with EPFL
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Related publications (7)
Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.
Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers
Sandrine Gerber, Inmaculada Robina, Gérald Coste
Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for analogues with better pharmacological profiles. The synthesis of 2-deoxystreptamine (2-DOS) dimers linked by polyamines and analogues bas ...
2011New efficient synthetic routes toward functionalised polyketides
RNA plays key roles in essential biological processes, such as protein synthesis, transcriptional regulation, splicing and retroviral replication. The structural diversity of RNA molecules and the lack of known RNA repair mechanisms make these biopolymers ...
EPFL2007Efficient synthesis of cyclic glycolipids analogues
A straightforward approach to macrocyclic structures containing deoxysugar subunits was developed through the functionalization of a bishemiketal. The choice of the length and the nature of the linkers can provide macrocycles with diverse rigidities and po ...
2007