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The electrochemical processes that underlie neural function manifest themselves in ceaseless spatiotemporal field fluctuations. However, extracellular fields feed back onto the electric potential across the neuronal membrane via ephaptic coupling, independ ...
The patch-clamp technique is today the most well-established method for recording electrical activity from individual neurons or their subcellular compartments. Nevertheless, achieving stable recordings, even from individual cells, remains a time-consuming ...
Neuronal circuitry is often considered a clean slate that can be dynamically and arbitrarily molded by experience. However, when we investigated synaptic connectivity in groups of pyramidal neurons in the neocortex, we found that both connectivity and syna ...
Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for organizing trained and untrained neural networks. In one aspect, a neural network device includes a collection of node assemblies interconnected by betwe ...
Interactions among neurons can take place in a wide variety of forms. It is the goal of this thesis to investigate the properties and implications of a number of these interactions that we believe are relevant for information processing in the brain. Neuro ...
EPFL2010
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Inhibitory pathways are an essential component in the function of the neocortical microcircuitry. Despite the relatively small fraction of inhibitory neurons in the neocortex, these neurons are strongly activated due to their high connectivity rate and the ...
Public Library of Science2010
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The general structure of the mammalian neocortex is remarkably similar across different cortical areas. Despite certain cytoarchitectural specializations and deviations from the general blueprint, the principal organization of the neocortex is relatively u ...