Publications by Marie-Stéphanie Camus

Amyloid ß-derived switch-peptides as tool to study conformational changes relevant in degenerative diseases

The rapid growing number of patients diagnosed with a neurodegenerative disease and more particularly with Alzheimer's disease (AD) has stimulated intensive research in determining and understanding biological phenomena causing such devastating diseases an ...

EPFL2008

Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept

Hilal Lashuel, Adrian Schmid, Richard Alan Mimna, Marie-Stéphanie Camus

Reversal of amyloid formation through a controlled induced transformation from beta-sheet to sol. alpha-helix structures through the use of a switch element S could have an important consequences understanding the mechanisms of amyloid formation and cleara ...

Wiley-VCH Verlag GmbH2007

Switch-peptides as folding precursors in self-assembling peptides and amyloid fibrillogenesis

Hilal Lashuel, Adrian Schmid, Karine Murat, Richard Alan Mimna, Marie-Stéphanie Camus, Jérémy Bérard

The study of conformational transitions of peptides has obtained considerable attention recently because of their importance as a mol. key event in a variety of degenerative diseases. However, the study of peptide self-assembly into beta-sheets and amyloid ...

2007

Switch-peptides: from conformational studies to Alzheimer's disease

Hilal Lashuel, Karine Murat, Richard Alan Mimna, Jacques Dubochet, Lydiane Jeanine Saucède, Sonia Dos Santos, Marie-Stéphanie Camus, Jérémy Bérard

A review. Studies on designed peptides that exhibit high tendencies for medium-induced conformational transitions have recently attracted much attention because structural changes are considered as mol. key processes in degenerative diseases. The exptl. ac ...

2006

Switch-peptides as folding precursors in amyloid fibrillogenesis

Sonia Dos Santos, Richard Alan Mimna, Karine Murat, Lydiane Jeanine Saucède, Marie-Stéphanie Camus, Jérémy Bérard

Intramol. O,N-acyl migration reactions were used as structural switch (S-elements) from a depsipeptide bond contg., unfolded state (Soff) to an all-amide, native states (Son). Chem. or enzymically triggered acyl migrations allowed for the controlled induct ...

2006

Switch on amyloid beta peptide self-assembly by enzyme-triggered acyl migration

Sonia Dos Santos, Richard Alan Mimna, Karine Murat, Lydiane Jeanine Saucède, Marie-Stéphanie Camus

2005