Olaf Blanke

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Cerebral amyloid angiopathy in patients with Dementia with Lewy Bodies: A clinical and hippocampal morphology study

Introduction: Dementia with Lewy Bodies (DLB) is often associated with Cerebral Amyloid Angiopathy (CAA) based on pathological studies. Current literature in DLB reveals heterogenous findings regarding CAA effects on cognition, but overall suggests a diffu ...

2025

Neuronal responses in the human primary motor cortex coincide with the subjective onset of movement intention in brain-machine interface-mediated actions

Olaf Blanke, Marco Solcà, Pavo Orepic

Self-initiated behavior is accompanied by the experience of intending our actions. Here, we leverage the unique opportunity to examine the full intentional chain-from intention to action to environmental effects-in a tetraplegic person outfitted with a pri ...

2025

Changes in spatial self-consciousness elicit grid cell–like representation in the entorhinal cortex

Olaf Blanke, Emanuela De Falco, Baptiste Gauthier, Louis Philippe Albert, Hyeongdong Park, Hyukjun Moon, Corentin Marie Hervé Robert Tasu

Grid cells in the entorhinal cortex (EC) encode an individual’s location in space, integrating both environmental and multisensory bodily cues. Notably, body-derived signals are also primary signals for the sense of self. While studies have demonstrated th ...

2024

Real-time fMRI neurofeedback modulates induced hallucinations and underlying brain mechanisms

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Jevita Potheegadoo, Herberto Dhanis Pedro De Barros Camacho, Elenor Morgenroth, Nicolas Gninenko, Nathan Quentin Faivre, Giulio Rognini

Hallucinations can occur in the healthy population, are clinically relevant and frequent symptoms in many neuropsychiatric conditions, and have been shown to mark disease progression in patients with neurodegenerative disorders where antipsychotic treatmen ...

Springer Science and Business Media LLC2024

Customizing the human-avatar mapping based on EEG error related potentials during avatar-based interaction

Olaf Blanke, José del Rocio Millán Ruiz, Ronan Boulic, Bruno Herbelin, Ricardo Andres Chavarriaga Lozano, Fumiaki Iwane, Thibault Serge Mario Porssut

Objective. A key challenge of virtual reality (VR) applications is to maintain a reliable human-avatar mapping. Users may lose the sense of controlling (sense of agency), owning (sense of body ownership), or being located (sense of self-location) inside th ...

2024

Numerosity estimation of virtual humans as a digital-robotic marker for hallucinations in Parkinson’s disease

Olaf Blanke, Bruno Herbelin, Fosco Bernasconi, Jevita Potheegadoo, Louis Philippe Albert

Nature Research2024

Out-of-body experiences in relation to lucid dreaming and sleep paralysis: A theoretical review and conceptual model

Olaf Blanke, Hsin-Ping Wu

Out-of-body experiences (OBEs) are characterized by the subjective experience of being located outside the physical body. Little is known about the neurophysiology of spontaneous OBEs, which are often reported by healthy individuals as occurring during sta ...

Elsevier BV2024

Noninvasive modulation of the hippocampal-entorhinal complex during spatial navigation in humans

Olaf Blanke, Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis, Elena Beanato, Esra Neufeld, Emanuela De Falco, Fabienne Windel, Maximilian Jonas Wessel, Traian Popa, Baptiste Gauthier

Because of the depth of the hippocampal-entorhinal complex (HC-EC) in the brain, understanding of its role in spatial navigation via neuromodulation was limited in humans. Here, we aimed to better elucidate this relationship in healthy volunteers, using tr ...

American Association for the Advancement of Science (AAAS)2024

Embodiment in episodic memory through premotor-hippocampal coupling

Olaf Blanke, Bruno Herbelin, Jevita Potheegadoo, Mariana Babo Rebelo, Nathalie Heidi Meyer, Baptiste Gauthier, Florian Lance

Episodic memory (EM) allows us to remember and relive past events and experiences and has been linked to cortical-hippocampal reinstatement of encoding activity. While EM is fundamental to establish a sense of self across time, this claim and its link to t ...

Springer Science and Business Media LLC2024

Numerosity estimation impairment measurement system

Olaf Blanke, Bruno Herbelin, Fosco Bernasconi, Jevita Potheegadoo, Louis Philippe Albert

Numerosity estimation impairment measurement system for diagnostic/prognosis of a neurologi- cal disorder comprising an electronic display device configured to present 3D scene representa- tions/images comprising a plurality of 3D virtual visual stimulus t ...

2024

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Neuronal responses in the human primary motor cortex coincide with the subjective onset of movement intention in brain-machine interface-mediated actions

Olaf Blanke, Marco Solcà, Pavo Orepic

2025