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Irina Baltcheva

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

A Generalized Mathematical Model To Estimate T- and B-Cell Receptor Diversities Using AmpliCot

Jean-Yves Le Boudec, Irina Baltcheva

The efficiency of the adaptive immune system is dependent on the diversity of T- and B-cell receptors, which is created by random rearrangement of receptor gene segments. AmpliCot is an experimental technique that allows the measurement of the diversity of ...

Elsevier2012

Mathematical Modeling of T-Cell Experimental Data

Irina Baltcheva

T lymphocytes (T cells) are key components of the adaptive immune system. These cells are able to recognize an enormous variety of pathogens thanks to the great specificity of their trans-membrane proteins, the T cell receptors (TCRs). TCR diversity is cre ...

EPFL2010

Lifelong dynamics of human CD4+CD25+ regulatory T cells: Insights from in vivo data and mathematical modeling

Jean-Yves Le Boudec, Irina Baltcheva

Despite their limited proliferation capacity, regulatory T cells (T(regs)) constitute a population maintained over the entire lifetime of a human organism. The means by which T(regs) sustain a stable pool in vivo are controversial. Using a mathematical mod ...

2010