Tyler Nerton Thacher

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Related publications (12)

Effects of reduced cyclic stretch on vascular smooth muscle cell function of pig carotids perfused ex vivo

Nikolaos Stergiopoulos, Paolo Silacci, Tyler Nerton Thacher, Veronica Gambillara

With advancing age arteries stiffen, reducing arterial compliance and leading to the development of systolic hypertension and to a substantial increase in pulse pressure. An augmented pulse pressure can be a predictor of the development of hypertension, wh ...

Oxford University Press2008

Oscillatory shear stress and reduced compliance impair vascular functions

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Paolo Silacci, Tyler Nerton Thacher, Veronica Gambillara

Shear stress has been shown to influence endothelial cell gene expression and morphology. In particular, low and bi-directional shear stress, mimicking conditions at plaque-prone areas, down-regulates the expression of several atheroprotective genes, and u ...

2007