Publications by Van Jay Wedeen

White matter maturation reshapes structural connectivity in the late developing human brain

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Leila Cammoun, Olaf Sporns, Van Jay Wedeen

From toddler to late teenager, the macroscopic pattern of axonal projections in the human brain remains largely unchanged while undergoing dramatic functional modifications that lead to network refinement. These functional modifications are mediated by inc ...

National Academy of Sciences2010

Diffusion Spectrum Imaging Shows the Structural Basis of Functional Cerebellar Circuits in the Human Cerebellum In Vivo

Reto Meuli, Cristina Granziera, Nouchine Hadjikhani, Van Jay Wedeen

Background: The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits. Identifying the structural bases of cerebellar neuronal networks in humans in vi ...

2009

Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers

Pascal Hagmann, Patric Hagmann, Van Jay Wedeen

MRI tractography is the mapping of neural fiber pathways based on diffusion MRI of tissue diffusion anisotropy. Tractography based on diffusion tensor imaging (DTI) cannot directly image multiple fiber orientations within a single voxel. To address this li ...

Elsevier2008

Quantitative Validation of MR Tractography Using the CoCoMac Database

Reto Meuli, Patric Hagmann, Xavier Gigandet, Olaf Sporns, Van Jay Wedeen

2008

Mapping Human Whole-Brain Structural Networks with Diffusion MRI

Jean-Philippe Thiran, Patrick Thiran, Reto Meuli, Patric Hagmann, Xavier Gigandet, Maciej Kurant, Van Jay Wedeen

Understanding the large-scale structural network formed by neurons is a major challenge in system neuroscience. A detailed connectivity map covering the entire brain would therefore be of great value. Based on diffusion MRI, we propose an efficient methodo ...

2007

Deriving scalar maps from Diffusion Spectrum MRI

Jean-Philippe Thiran, Patric Hagmann, Reto Meuli, Leila Cammoun, Xavier Gigandet, Van Jay Wedeen

Whole brain DSI acquisitions are now clinically feasible. It is therefore necessary to have scalar maps available in order to easily visualize summary statistics of the full 3D diffusion pdf available in every voxel. We show how to derive from DSI not only ...

IEEE2007

Representing Diffusion MRI in 5D Simplifies Regularization and Segmentation of White Matter Tracts

Jean-Philippe Thiran, Patric Hagmann, Xavier Bresson, Lisa Jonasson, Van Jay Wedeen

Institute of Electrical and Electronics Engineers2007

Understanding Diffusion MR Imaging Techniques: From Scalar Diffusion-weighted Imaging to Diffusion Tensor Imaging and Beyond

Jean-Philippe Thiran, Patric Hagmann, Reto Meuli, Lisa Jonasson, Van Jay Wedeen

The complex structural organization of the white matter of the brain can be depicted in vivo in great detail with advanced diffusion magnetic resonance (MR) imaging schemes. Diffusion MR imaging techniques are increasingly varied, from the simplest and mos ...

2006

Fibertract segmentation in position orientation space from high angular resolution diffusion MRI

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Lisa Jonasson, Van Jay Wedeen, Thomas Deffieux

In diffusion MRI, standard approaches for fibertract identification are based on algorithms that generate lines of coherent diffusion, currently known as tractography. A tract is then identified as a set of such lines selected on some criteria. In the pres ...

2006