Person
Matthieu Jean-Hubert Delincé
This person is no longer with EPFL
Related publications (4)
A microfluidic cell-trapping device to study dynamic host-microbe interactions at the single-cell level
John McKinney, Matthieu Jean-Hubert Delincé, Chiara Toniolo
Single-cell imaging of host-microbe interactions over time is impeded by cellular motility because the cells under scrutiny tend to migrate out of the imaging field. To overcome this technical challenge, we developed a microfluidic platform for imaging hun ...
ELSEVIER ACADEMIC PRESS INC2018Quantitative Single-Cell Analysis of Host-Pathogen Interactions
During infection, microbial pathogens encounter phagocytic cells of the host innate immune system, such as macrophages and neutrophils. These encounters typically lead to uptake and killing of the bacteria by the host cell or, conversely, parasitization of ...
EPFL2016A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions
John McKinney, Jean-Baptiste Bureau, Matthieu Jean-Hubert Delincé, Thierry Soldati
The impact of cellular individuality on host-microbe interactions is increasingly appreciated but studying the temporal dynamics of single-cell behavior in this context remains technically challenging. Here we present a microfluidic platform, InfectChip, t ...
Royal Society of Chemistry2016The Role of c-di-AMP in Listeria monocytogenes
L. monocytogenes is a Gram-positive intracellular pathogen that can cause serious disease, like septicemia and meningitis. It is detected in the cytosol by the innate immune system by sensing pathogen ligands. c-di-AMP has recently been shown to be one of ...
2011