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David Paul Roger Romascano

Related publications (32)

Successful MRI-Guided Focused Ultrasound Thalamotomy after Ipsilateral Gamma Knife Radiosurgery for Essential Tremor: A Case Report with Video

Constantin Tuleasca, David Paul Roger Romascano, Damien Schneider

We report the case of a 67-year-old left-handed female patient with disabling medically refractory essential tremor who underwent successful right-sided magnetic resonance-guided focused ultrasound (MRgFUS) of the ventral intermediate nucleus after ipsilat ...

Basel2023

Bundle-Specific Axon Diameter Index as a New Contrast to Differentiate White Matter Tracts

Jean-Philippe Thiran, Gabriel Girard, David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Muhamed Barakovic, Maxime Descoteaux, Giorgio Innocenti

In the central nervous system of primates, several pathways are characterized by different spectra of axon diameters. In vivo methods, based on diffusion-weighted magnetic resonance imaging, can provide axon diameter index estimates non-invasively. However ...

2021

Tractostorm: The what, why, and how of tractography dissection reproducibility

Gabriel Girard, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux

Investigative studies of white matter (WM) brain structures using diffusion MRI (dMRI) tractography frequently require manual WM bundle segmentation, often called "virtual dissection." Human errors and personal decisions make these manual segmentations har ...

2020

Robust Monte-Carlo Simulations in Diffusion-MRI: Effect of the Substrate Complexity and Parameter Choice on the Reproducibility of Results

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, David Paul Roger Romascano, Alonso Ramirez Manzanares

Monte-Carlo Diffusion Simulations (MCDS) have been used extensively as a ground truth tool for the validation of microstructure models for Diffusion-Weighted MRI. However, methodological pitfalls in the design of the biomimicking geometrical configurations ...

2020

Towards non-parametric reconstruction of axon diameter distributions using diffusion MRI and regularized discrete linear modeling

David Paul Roger Romascano

The distribution of axon diameters (ADD) is an important white matter feature: it influences action potential speed, it has been shown to evolve during development, and also to be affected during pathological processes. Diffusion Magnetic Resonance Imaging ...

EPFL2019

Sparse wars: A survey and comparative study of spherical deconvolution algorithms for diffusion MRI

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, David Paul Roger Romascano, Marco Pizzolato, Jonathan Rafael Patino Lopez, Alessandro Daducci, Muhamed Barakovic, Gaëtan Olivier D Rensonnet

Spherical deconvolution methods are widely used to estimate the brain's white-matter fiber orientations from diffusion MRI data. In this study, eight spherical deconvolution algorithms were implemented and evaluated. These included two model selection tech ...

2019

ActiveAx(ADD): Toward non-parametric and orientationally invariant axon diameter distribution mapping using PGSE

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Tim Bjørn Dyrby

Purpose Non-invasive axon diameter distribution (ADD) mapping using diffusion MRI is an ill-posed problem. Current ADD mapping methods require knowledge of axon orientation before performing the acquisition. Instead, ActiveAx uses a 3D sampling scheme to e ...

2019

HOTmix: characterizing hindered diffusion using a mixture of generalized higher order tensors

We present HOTmix, a new model to describe the diffusion MRI signal for molecules undergoing hindered diffusion. HOTmix is based on a mixture of generalized higher order tensors, explicitly incorporating the diffusion sequence’s time-dependent parameters. ...

2019

Central nervous system microbleeds in the acute phase are associated with structural integrity by DTI one year after mild traumatic brain injury: A longitudinal study

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Pietro Bontempi

Introduction: Several imaging modalities are under investigation to unravel the pathophysiological mystery of delayed performance deficits in patients after mild traumatic brain injury (mTBI). Although both imaging and neuropsychological studies have been ...

ELSEVIER URBAN & PARTNER SP Z O O2018

Assessing feasibility and reproducibility of a bundle-specific framework on in vivo axon diameter estimates at 300mT/m

Jean-Philippe Thiran, Gabriel Girard, David Paul Roger Romascano, Jonathan Rafael Patino Lopez, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux, Giorgio Innocenti

In vivo quantitative estimation of axon diameter in the white matter could bring new tools to study the structural and functional architecture of the brain. Recently, the feasibility of axon diameter estimation with diffusion-weighted MRI (DW-MRI) has been ...

2018

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