Publications by Simone Ulzega | EPFL Graph Search

Broadband excitation in solid-state NMR using interleaved DANTE pulse trains with N pulses per rotor period

Geoffrey Bodenhausen, Diego Carnevale, Simone Ulzega

We analyze the direct excitation of wide one-dimensional spectra of nuclei with spin I = 1/2 or 1 in rotating solids submitted to pulse trains in the manner of Delays Alternating with Nutations for Tailored Excitation (DANTE), either with one short rotor-s ...

Academic Press Inc - Elsevier Science2013

Procédé pour spectroscopie RMN d'échantillons solides

Geoffrey Bodenhausen, Simone Ulzega, Marc Anthony Caporini

A method for performing magnetic resonance spectroscopy on solid sample containing nuclei of interest with spin quantum number I, comprising: subjecting the sample to a static magnetic field, spinning the sample at the magic angle and broad-band excitation ...

2013

Boosting the Sensitivity of Ligand-Protein Screening by NMR of Long-Lived States

Geoffrey Bodenhausen, Christian Heinis, Aurélien Bornet, Inmaculada Rentero Rebollo, Alessandro Angelini, Simone Ulzega, Nicola Salvi, Roberto Buratto

A new NMR method for the study of ligand protein interactions exploits the unusual lifetimes of long-lived states (LLSs). The new method provides better contrast between bound and free ligands and requires a protein-ligand ratio ca. 25 times lower than for ...

2012

Dynamic Nuclear Polarization and Other Magnetic Ideas at EPFL

Geoffrey Bodenhausen, Aurélien Bornet, Pascal Miéville, Sami Jannin, Jonas Milani, Diego Carnevale, Simone Ulzega, Marc Anthony Caporini, Nicola Salvi, Daniele Mammoli

Although nuclear magnetic resonance (NMR) can provide a wealth of information, it often suffers from a lack of sensitivity. Dynamic Nuclear Polarization (DNP) provides a way to increase the polarization and hence the signal intensities in NMR spectra by tr ...

2012

Uniform broadband excitation of crystallites in rotating solids using interleaved sequences of delays alternating with nutation

Geoffrey Bodenhausen, Simone Ulzega, Marc Anthony Caporini

In solids that are spinning about the magic angle, trains of short pulses in the manner of Delays Alternating with Nutations for Tailored Excitation (DANTE) allow one to improve the efficiency of the excitation of magnetization compared to rectangular puls ...

Academic Press Inc - Elsevier Science2012

Time Scales of Slow Motions in Ubiquitin Explored by Heteronuclear Double Resonance

Geoffrey Bodenhausen, Simone Ulzega, Nicola Salvi, Fabien Ferrage

Understanding how proteins function at the atomic level relies in part on a detailed characterization of their dynamics. Ubiquitin, a small single-domain protein, displays rich dynamic properties over a wide range of time scales. In particular, several reg ...

2012

Broadband excitation and indirect detection of nitrogen-14 in rotating solids using Delays Alternating with Nutation (DANTE)

Geoffrey Bodenhausen, Simone Ulzega, Marc Anthony Caporini

A train of short rotor-synchronized pulses in the manner of Delays Alternating with Nutations for Tailored Excitation (DANTE) applied to nitrogen-14 nuclei (I = 1) in samples spinning at the magic angle at high frequencies (typically nu(rot) = 62.5 kHz so ...

Academic Press Inc - Elsevier Science2011

Preservation of heteronuclear multiple-quantum coherences in NMR by double-resonance irradiation

Geoffrey Bodenhausen, Mariachiara Verde, Simone Ulzega, Fabien Ferrage

A heteronuclear double-resonance (HDR) method based on MLEV-32 or WALTZ-32 pulse sequences has been designed for the investigation of relaxation of heteronuclear multiple-quantum (MQ) coherences. The theoretical analysis of this technique uses average Hami ...

2009

Heteronuclear Double Resonance in NMR Spectroscopy: Relaxation of Multiple Quantum Coherences

Geoffrey Bodenhausen, Mariachiara Verde, Simone Ulzega, Fabien Ferrage

Theoretical and experimental investigations of the relaxation rates of multiple-quantum coherences during heteronuclear double resonance (HDR) pulse sequences are presented. Average Liouvillian theory yields analytical expressions to describe the effective ...

2009

Lifetime of the Cs6P(1/2) state in bcc and hcp solid He-4

Simone Ulzega

We present the first experimental study of time-resolved fluorescence from laser-excited Cs(6P(1/2)) atoms isolated in a solid He-4 matrix. The results are compared to the predictions of the bubble model including the interaction of the atomic dipole with ...

2008