Publications by Tobias Kober | EPFL Graph Search

Domain shift, domain adaptation, and generalization: A focus on MRI

Meritxell Bach Cuadra, Tobias Kober, Veronica Lily Ravano, Jonas Richiardi

Differences in acquisition protocols or hardware result in measurable changes in image characteristics. These differences affect distributional properties and can also affect the spatial and temporal characteristics of the images. Likewise, the distributio ...

Academic Press2025

A noninvasive accelerated quantitative MR technique to distinguish drug resistance in prolactinomas: Early results

Tobias Kober

Management of dopamine agonist (DA) resistance in prolactinoma (PRLoma) remains challenging due to the lack of detecting approach and reliable imaging marker. In this cross-sectional study, PRLoma patients were recruited prospectively from a single-center ...

2025

Diffusion Imaging Protocol Heterogeneity Biases Ischemic Core Volume, Location, and Clinical Associations in Acute Stroke

Tobias Kober, Veronica Lily Ravano

BACKGROUND: Diffusion-weighted magnetic resonance imaging is essential for diagnosing ischemic stroke and identifying targets for emergency revascularization. Apparent diffusion coefficient (ADC) maps derived from diffusion-weighted magnetic resonance imag ...

LIPPINCOTT WILLIAMS & WILKINS2025

To evaluate repaired rotator cuff morphologically and quantitatively in one GRAPPATINI MRI examination

Tobias Kober, Tom Hilbert

Background: GRAPPATINI is capable of originating synthetic T2 images (T2(synth)) and T2 maps in one magnetic resonance imaging (MRI) scan. Purpose: To evaluate GRAPPATINI's performance in providing simultaneous morphological assessment of repaired rotator ...

SAGE PUBLICATIONS LTD2025

Improved MR Detection of Optic Nerve Demyelination With MP2RAGE-FLAWS Compared With T2-Weighted Fat-Saturated Sequences

Tobias Kober

Objectives: Nonenhanced T1-w sequences such as magnetization-prepared 2 rapid acquisition gradient echo (MP2RAGE) and derived fluid and white matter suppression (FLAWS) have demonstrated high performance for detecting brain parenchymal and cervical spine d ...

2024

Precision brain morphometry using cluster scanning

Tobias Kober, Tom Hilbert

Measurement error limits the statistical power to detect group differences and longitudinal change in structural MRI morphometric measures (e.g., hippocampal volume, prefrontal cortical thickness). Recent advances in scan acceleration enable extremely fast ...

2024

Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol

Tobias Kober, Tom Hilbert

The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The acqui ...

ELSEVIER SCI LTD2024

Advancing Thalamic Nuclei Segmentation: The Impact of Compressed Sensing on MRI Processing

Tobias Kober, Tom Hilbert

The thalamus is a collection of gray matter nuclei that play a crucial role in sensorimotor processing and modulation of cortical activity. Characterizing thalamic nuclei non-invasively with structural MRI is particularly relevant for patient populations w ...

Wiley2024

Normative volumes and relaxation times at 3T during brain development

Tobias Kober, Tom Hilbert, Bénédicte Marie Maréchal, Ricardo Alberto Corredor Jerez

While research has unveiled and quantified brain markers of abnormal neurodevelopment, clinicians still work with qualitative metrics for MRI brain investigation. The purpose of the current article is to bridge the knowledge gap between case-control cohort ...

Nature Portfolio2024

Fast refacing of MR images with a generative neural network lowers re-identification risk and preserves volumetric consistency

Jean-Philippe Thiran, Tobias Kober, Bénédicte Marie Maréchal

With the rise of open data, identifiability of individuals based on 3D renderings obtained from routine structural magnetic resonance imaging (MRI) scans of the head has become a growing privacy concern. To protect subject privacy, several algorithms have ...

Wiley2024