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Neeraj Dhar

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Courses taught by this person (1)

Related publications (54)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

HUM-125(b): Global issues: health B

Le cours présente l'enjeu mondial de la santé. Il aborde les défis posés par l'innovation biomédicale, les maladies infectieuses et neuropsychiatriques. L'approche interdisciplinaire intègre les SHS e

Investigating the composition and recruitment of the mycobacterial ImuA'-ImuB-DnaE2 mutasome

John McKinney, Neeraj Dhar, Zela Alexandria-Mae Martin

A DNA damage-inducible mutagenic gene cassette has been implicated in the emergence of drug resistance in Mycobacterium tuberculosis during anti-tuberculosis (TB) chemotherapy. However, the molecular composition and operation of the encoded 'mycobacterial ...

Elife Sciences Publ Ltd2023

Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking

IntroductionMycobacteria assemble a complex cell wall with cross-linked peptidoglycan (PG) which plays an essential role in maintenance of cell wall integrity and tolerance to osmotic pressure. We previously demonstrated that various hydrolytic enzymes are ...

FRONTIERS MEDIA SA2023

Mechanopathology of biofilm-like Mycobacterium tuberculosis cords

John McKinney, Graham Knott, Neeraj Dhar, Nicolas Jean Philippe Guex, Jessica Sordet, Maxime Jan, Richa Mishra, Mélanie Thérèse Marie Hannebelle, Vivek Vijay Thacker, Kunal Sharma

Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in alveolar cells contribute to suppression of innate immune signaling via nu ...

Cell Press2023