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Özgür Genç

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Role of Protein Kinase C and Munc18-1 in a Presynaptic Form of Plasticity, Post-tetanic Potentiation

Neurons are arranged in networks in which they communicate between each other by the means of synapses. Synaptic transmission can undergo activity-dependent and short-lived changes in strength, known as short-term synaptic plasticity. Short-term plasticity ...

EPFL2013

Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

Ralf Schneggenburger, Olexiy Kochubey, Özgür Genç

Transmitter release at synapses is regulated by preceding neuronal activity, which can give rise to short-term enhancement of release like post-tetanic potentiation (PTP). Diacylglycerol (DAG) and Protein-kinase C (PKC) signaling in the nerve terminal have ...

Elife Sciences Publications Ltd2014

Nigrostriatal overabundance of alpha-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity

Patrick Aebischer, Graham Knott, Marco Cantoni, Ralf Schneggenburger, Özgür Genç, Jean-Charles Bensadoun, Wojciech Janusz Bobela, Safa Mohanna

alpha-Synuclein (alpha-syn) is a presynaptic protein present at most nerve terminals, but its function remains largely unknown. The familial forms of Parkinson's disease associated with multiplications of the alpha-syn gene locus indicate that overabundanc ...

Springer-Verlag2012