Publications by Sophie Marie Marthe Wurth

Bayesian optimization of peripheral intraneural stimulation protocols to evoke distal limb movements

Silvestro Micera, Grégoire Courtine, Simon Borgognon, Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois

Objective. Motor neuroprostheses require the identification of stimulation protocols that effectively produce desired movements. Manual search for these protocols can be very time-consuming and often leads to suboptimal solutions, as several stimulation pa ...

IOP Publishing Ltd2021

Intrafascicular peripheral nerve stimulation produces fine functional hand movements in primates

Silvestro Micera, Grégoire Courtine, Simon Borgognon, Evgenia Vladimirova Roussinova, Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois

Restoring dexterous hand control is critical for people with paralysis. Approaches based on surface or intramuscular stimulation provide limited finger control, generate insufficient force to recover functional movements, and require numerous electrodes. H ...

AMER ASSOC ADVANCEMENT SCIENCE2021

A versatile robotic platform for the design of natural, three-dimensional reaching and grasping tasks in monkeys

Aude Billard, Silvestro Micera, Marco Capogrosso, Seyed Sina Mirrazavi Salehian, Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Sara Conti

Objective. Translational studies on motor control and neurological disorders require detailed monitoring of sensorimotor components of natural limb movements in relevant animal models. However, available experimental tools do not provide a sufficiently ric ...

IOP PUBLISHING LTD2020

A neurostimulation system for central nervous stimulation (cns) and peripheral nervous stimulation (pns)

Silvestro Micera, Grégoire Courtine, Sophie Marie Marthe Wurth

The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stim ...

2018

Closed-loop control of trunk posture improves locomotion through the regulation of leg proprioceptive feedback after spinal cord injury

Silvestro Micera, Grégoire Courtine, Eduardo Martin Moraud, Joachim von Zitzewitz, Jenifer Cléa Miehlbradt, Marco Capogrosso, Sophie Marie Marthe Wurth, Emanuele Formento

Nature Research2018

Hybrid peripheral-spinal neuroprosthesis for refined motor execution after paralysis

Sophie Marie Marthe Wurth

Spinal cord injury (SCI) disrupts the communication between the brain and the spinal circuits responsible for movement, thereby causing severe motor deficits. Current strategies to restore function to paralyzed limbs have separately investigated electrical ...

EPFL2018

Long-term usability and bio-integration of polyimide-based intraneural stimulating electrodes

Silvestro Micera, Grégoire Courtine, Nawal Noëlle Kinany, Quentin Barraud, Marco Capogrosso, Stanisa Raspopovic, Sophie Marie Marthe Wurth, Alessandra Piersigilli, Jacopo Rigosa, Jérôme Gandar

Stimulation of peripheral nerves has transiently restored lost sensation and has the potential to alleviate motor deficits. However, incomplete characterization of the long-term usability and bio-integration of intra-neural implants has restricted their us ...

Elsevier Sci Ltd2017

Rehabilitative Soft Exoskeleton for Rodents

Silvestro Micera, Grégoire Courtine, Jamie Paik, Eduardo Martin Moraud, Joachim von Zitzewitz, Sophie Marie Marthe Wurth, Rubia van den Brand, Juan Manuel Florez Marin, Laetitia Danielle Philippine Baud, Manan Kishore Shah

Robotic exoskeletons provide programmable, consistent and controllable active therapeutic assistance to patients with neurological disorders. Here we introduce a prototype and preliminary experimental evaluation of a rehabilitative gait exoskeleton that en ...

Institute of Electrical and Electronics Engineers2016

Chronic multichannel neural recordings from soft regenerative microchannel electrodes during gait

Silvestro Micera, Stéphanie Lacour, Marco Capogrosso, Jacopo Rigosa, Sophie Marie Marthe Wurth, Shreya Narasimhan, Katherine Marie Musick

Reliably interfacing a nerve with an electrode array is one of the approaches to restore motor and sensory functions after an injury to the peripheral nerve. Accomplishing this with current technologies is challenging as the electrode-neuron interface ofte ...

Nature Publishing Group2015

A real-time comparison between direct control, sequential pattern recognition control and simultaneous pattern recognition control using a Fitts' law style assessment procedure

Sophie Marie Marthe Wurth

Background: Pattern recognition (PR) based strategies for the control of myoelectric upper limb prostheses are generally evaluated through offline classification accuracy, which is an admittedly useful metric, but insufficient to discuss functional perform ...

BioMed Central2014