Publications by Xile Hu | EPFL Graph Search

Encapsulated Co–Ni alloy boosts high-temperature CO2 electroreduction

Xile Hu, Jeremy Luterbacher, Seongmin Jin, Wenhao Ren

Electrochemical CO 2 reduction into chemicals and fuels holds great promise for renewable energy storage and carbon recycling 1–3 . Although high-temperature CO 2 electroreduction in solid oxide electrolysis cells is industrially relevant, current catalyst ...

Springer Science and Business Media LLC2025

Artificial Metalloenzymes with Two Catalytic Cofactors for Tandem Abiotic Transformations

Xile Hu, Florence Pojer, Kelvin Ka Ching Lau, Weijin Wang

Artificial metalloenzymes (ArMs) enable the integration of abiotic cofactors within a native protein scaffold, allowing for non-natural catalytic activities. Previous ArMs, however, have primarily relied on single cofactor systems, limiting them to only on ...

Wiley-VCH Verlag GmbH2025

Anion Exchange Membrane Water Electrolysis at 10 A ⋅ cm−2 Over 800 Hours

Xile Hu, Ariana Serban, Yiwei Zheng

Anion exchange membrane water electrolyzer (AEMWE) is a potentially cost-effective technology for green hydrogen production. Although the normal current densities of AEMWEs are below 3 A ⋅ cm−2, operating them at higher current densities represents an effi ...

Wiley-VCH Verlag GmbH2025

Encapsulated alloy catalysts and their methods of preparation

Xile Hu

The present invention relates to a method for preparing a catalyst comprising the steps of a. dissolving two or more alloy metal salts, b. adding at least one chelating agent and at least one stabilising agent, forming a sol, c. adding an encapsulant to ...

2025

Enantioconvergent Cobalt‐Catalyzed Hydroalkylation for the Construction of Fluoro‐, Chloro‐, and Trifluoromethyl Stereogenic Centers

Xile Hu

Organic compounds containing a chiral, halogenated aliphatic carbon center are useful in medicinal chemistry, but their enantioselective synthesis remains difficult. Here we develop a general approach to access these compounds through cobalt‐catalyzed hydr ...

Wiley2025

Operando Nanoscale Characterization Reveals Fe Doping of Ni Oxide Enhances Oxygen Evolution Reaction via Fragmentation and Formation of Dual Active Sites

Xile Hu, Magalí Alejandra Lingenfelder, Yunchang Liang, Victor Carle Adrien Boureau, Seunghwa Lee, Karla Banjac

Efficient catalytic water splitting demands advanced catalysts to improve the slow kinetics of the oxygen evolution reaction (OER). Earth-abundant transition metal oxides show promising OER activity in alkaline media. However, most experimental information ...

2025

Strain by metal nitrides accelerates oxygen reduction

Xile Hu

Scrutinizing the metal nitride/oxide interface reveals the chemical origin of the enhanced oxygen reduction activity of metal nitrides. ...

NATURE PORTFOLIO2024

Field-enhanced CO electroreduction in membrane electrolyzers at a dehydrated interface

Xile Hu, Miyeon Chang, Nanjun Chen, Wenhao Ren

Zero-gap membrane electrode assembly (MEA) CO electrolyzer stands as a promising technology for circular carbon economy. However, current CO electrolyzers are energetically inefficient when operating at ampere-level current densities. Here, by analyzing th ...

2024

Regiodivergent and Enantioselective Synthesis of Cyclic Sulfones via Ligand-Controlled Nickel-Catalyzed Hydroalkylation

Xile Hu, Chao Fan, Deyun Qian

Cyclic sulfones have demonstrated important applications in drug discovery. However, the catalytic and enantioselective synthesis of chiral cyclic sulfones remains challenging. Herein, we develop nickel-catalyzed regiodivergent and enantioselective hydroal ...

Wiley-VCH Verlag GmbH2024

Nickel-Catalyzed Enantio- and Diastereoselective Synthesis of Fluorine-Containing Vicinal Stereogenic Centers

Xile Hu, Lara Lavrencic

The construction of fluorinated architectures has been a topic of interest to medicinal chemists due to their unique ability to improve the pharmacokinetic properties of bioactive compounds. However, the stereoselective synthesis of fluoro-organic compound ...

2024