Person
Qingxia Zhong
This person is no longer with EPFL
Related publications (11)
Cross-resistance of UV- or chlorine dioxide-resistant echovirus 11 to other disinfectants
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong, Rachele Ossola
The emergence of waterborne viruses with resistance to disinfection has been demonstrated in the laboratory and in the environment. Yet, the implications of such resistance for virus control remain obscure. In this study we investigate if viruses with resi ...
Frontiers Research Foundation2017Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Jeffrey David Jensen, Qingxia Zhong, Hyunjin Shim
Waterborne viruses can exhibit resistance to common water disinfectants, yet the mechanisms that allow them to tolerate disinfection are poorly understood. Here, we generated echovirus 11 (E11) with resistance to chlorine dioxide (ClO2) by experimental evo ...
Amer Chemical Soc2017Genotypic, phenotypic and mechanistic insights into viruses with resistance to common water disinfectants
Infectious diseases caused by waterborne viruses contribute to the global disease burden. An effective barrier to prevent the discharge of waterborne viruses is a disinfection step, yet disinfection is not always efficient at inactivating viruses. This the ...
EPFL2017Experimental adaptation of human echovirus 11 to ultraviolet radiation leads to tolerance to disinfection and resistance to ribavirin
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Jeffrey David Jensen, Qingxia Zhong, Hyunjin Shim
Ultraviolet light in the UVC range is a commonly used disinfectant to control viruses in clinical settings and water treatment. Here, we employed an experimental evolution approach to investigate the adaptation of human echovirus 11 to disinfection by UVC, ...
2017Genetic, structural and phenotypic properties of MS2 coliphage with resistance to ClO2 disinfection
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Sergey Nazarov, Petr Leiman, Qingxia Zhong, Ricardo Cesar Guerrero Ferreira, Laura Piccinini
Common water disinfectants like chlorine have been reported to select for resistant viruses, yet little attention has been devoted to characterizing disinfection resistance. Here, we investigated the resistance of MS2 coliphage to inactivation by chlorine ...
Amer Chemical Soc2016Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong
Disinfection is an important strategy to control the environmental transmission of human viruses. Specifically, UV254 is increasingly used to disinfect from clinical items or surfaces to drinking water. RNA virus populations have high mutation rates and la ...
2016Echovirus 11 mutants with increased resistance to common water disinfectants
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong
Common water disinfectants like chlorine have been reported to select for resistant viruses. Yet, only little attention has been devoted to characterizing disinfection resistance. The goal of this study was to produce disinfectant-resistant viruses and to ...
2016Echovirus 11 mutants with increased resistance to common water disinfectants
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong
Common water disinfectants like chlorine have been reported to select for resistant viruses. Yet, only little attention has been devoted to characterizing disinfection resistance. The goal of this study was to produce disinfectant-resistant viruses and to ...
2016Evolution and characterization of MS2 bacteriophage and echovirus 11 Resistance to disinfection by CLO2
Tamar Kohn, Anna Carratala Ripolles, Qingxia Zhong
In this study, we investigate if frequent exposure to disinfectants promotes the emergence of virus resistance to disinfectants. We found that repeated passages causes viruses gain increasing resistance toward ClO2. However, the role of ClO2 is not clear i ...
2015On the cause of the tailing phenomenon during virus disinfection by chlorine dioxide
Tamar Kohn, Qingxia Zhong, Anne Thérèse Sigstam, Moritz Brennecke, Andreas Rohatschek
This study investigates the mechanisms underlying the deviation from Chick-Watson kinetics, namely a tailing curve, during the disinfection of viruses by chlorine dioxide (ClO2). Tailing has been previously reported, but is typically attributed to the deca ...
Elsevier2014