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Jeffrey James Rice

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Related publications (4)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Tenascin C Promiscuously Binds Growth Factors via Its Fifth Fibronectin Type III-Like Domain

Jeffrey Alan Hubbell, Federico Tortelli, Jeffrey James Rice

Tenascin C (TNC) is an extracellular matrix protein that is upregulated during development as well as tissue remodeling. TNC is comprised of multiple independent folding domains, including 15 fibronectin type III-like (TNCIII) domains. The fifth TNCIII dom ...

Public Library of Science2013

Extracellular matrix heparin-binding domains

Jeffrey Alan Hubbell, Mikaël Martino, Federico Tortelli, Jeffrey James Rice

Heparin binding peptides derived from a Tenascin (TNC) III1-5 domain or a fibrinogen ²15-66 domain have been found that bind certain cytokines with high affinity. Materials and methods for making compositions and devices using these peptides are disclosed. ...

2015

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

Jeffrey Alan Hubbell, Melody Swartz, Mikaël Martino, Witold Waldemar Kilarski, Priscilla Suhasna Maithili Briquez, Esra Güç, Federico Tortelli, Stéphanie Elisabeth Metzger, Jeffrey James Rice

Growth factors (GFs) are critical in tissue repair, but their translation to clinical use has been modest. Physiologically, GF interactions with extracellular matrix (ECM) components facilitate localized and spatially regulated signaling; therefore, we rea ...

American Association for the Advancement of Science2014