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Alessandro Angelini

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Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

Macrocycle synthesis strategy based on step-wise “adding and reacting” three components enables screening of large combinatorial libraries

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

Phage display libraries of differently sized bicyclic peptides

Bicyclic Peptide inhibitor reveals large contact interface with a protease target

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

Phage display libraries of differently sized bicyclic peptides

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

Bicyclic Peptide inhibitor reveals large contact interface with a protease target

Macrocycle synthesis strategy based on step-wise “adding and reacting” three components enables screening of large combinatorial libraries