Publications by Hiroyasu Yamamoto

Search for a Light CP-odd Higgs Boson and Low-Mass Dark Matter at the Belle Experiment

Olivier Schneider, Yiming Li, Roberto Gargiani, Chao Wang, Mithilesh Nayak, Gaétan Charles Antoine Giriat, Tagir Aushev, Sun Hee Kim, Tara Nanut, Ke Huang

We report on the first Belle search for a light CP-odd Higgs boson, A(0), that decays into low mass dark matter, chi, in final states with a single photon and missing energy. We search for events produced via the dipion transition (sic)(2S) -> (sic)(1S)pi( ...

2019

Search for the rare decay of B+ -> l(+)nu e gamma with improved hadronic tagging

Olivier Schneider, Roberto Gargiani, Yiming Li, Mingkui Wang, Mithilesh Nayak, Chao Wang, Gaétan Charles Antoine Giriat, Sun Hee Kim, Tagir Aushev, Seyed Sina Mirrazavi Salehian

We present the result of the search for the rare B meson decay of B+ -> l(+)nu e gamma with l = e, mu. For the search the full data set recorded by the Belle experiment of 711 fb(-1) integrated luminosity near the Upsilon(4S) resonance is used. Signal cand ...

American Physical Society2018

Observation of e(+) e(-) -> gamma chi(c1) and search for e(+) e(-) -> gamma chi(c0), gamma chi(c2), and gamma eta(c) at root s near 10.6 GeV at Belle

Olivier Schneider, Yiming Li, Roberto Gargiani, Mingkui Wang, Gaétan Charles Antoine Giriat, Chao Wang, Sun Hee Kim, Tagir Aushev, Timothy Chi Hin Liew, Chang-Hyun Park

Using data samples of 89.5 fb(-1), 711.0 fb(-1), and 121.4 fb(-1) collected with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider at center-of-mass energies 10.52, 10.58, and 10.867 GeV, respectively, we study the exclusive reactions e(+) ...

American Physical Society2018

Search for the lepton-flavor-violating decay B-0 -> K-*0 mu(+/-)e(-/+)

Olivier Schneider, Yiming Li, Roberto Gargiani, Gaétan Charles Antoine Giriat, Mingkui Wang, Chao Wang, Sun Hee Kim, Tagir Aushev, Tara Nanut, Chang-Hyun Park

We have searched for the lepton-flavor-violating decay B-0 -> K-*0 mu(+/-)e(-/+) using a data sample of 711 fb(-1) that contains 772 x 10(6) B (B) over bar pairs. The data were collected near the Upsilon(4S) resonance with the Belle detector at the KEKB as ...

American Physical Society2018

Observation of e(+) e(-) -> pi(+) pi(-) pi(0)chi(b1,2) (1P) and search for e(+) e (-) -> phi chi(b1,2) (1P) at root s=10.96-11.05 GeV

Olivier Schneider, Yiming Li, Roberto Gargiani, Mingkui Wang, Gaétan Charles Antoine Giriat, Sun Hee Kim, Chao Wang, Tagir Aushev, Tara Nanut, Chang-Hyun Park

We report searches for the processes e(+) e(-) -> pi(+)pi(-)pi(0)chi(bJ) and e(+) e(-) -> phi chi(bJ) ( J = 1, 2) based on data samples collected by the Belle experiment at the KEKB collider. We report the first observation of the process e(+) e(-) -> (pi( ...

American Physical Society2018

SIRT2 Deficiency Modulates Macrophage Polarization and Susceptibility to Experimental Colitis

Johan Auwerx, Kristina Schoonjans, Alessia Perino, Adrienne Joëlle Laurence Mottis, Alessandra Piersigilli, Keir Joe Menzies, Hiroyasu Yamamoto, Giuseppe Lo Sasso

Background: SIRT2 belongs to a highly conserved family of NAD(+)-dependent deacylases, consisting of seven members (SIRT1-SIRT7), which vary in subcellular localizations and have substrates ranging from histones to transcription factors and enzymes. Recent ...

Public Library of Science2014

Ncor1 is a physiological modulator of muscle mass and oxidative function

Johan Auwerx, Laurent Mouchiroud, Hiroyasu Yamamoto

The present invention provides methods of increasing muscle mass and muscle miochodrial oxidative metabolism. Additionally, the invention provides treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic ...

2012

NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function

Johan Auwerx, Kristina Schoonjans, Carlos Canto Alvarez, Laurent Mouchiroud, Hiroyasu Yamamoto, Evan Graehl Williams

Transcriptional coregulators control the activity of many transcription factors and are thought to have wide-ranging effects on gene expression patterns. We show here that muscle-specific loss of nuclear receptor corepressor 1 (NCoR1) in mice leads to enha ...

2011

CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability

Johan Auwerx, Carlos Canto Alvarez, Chikage Mataki, Hiroyasu Yamamoto, Lilia Noriega Lopez, Jiujiu Yu

The nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase SIRT1 is a major metabolic regulator activated by energy stresses such as fasting or calorie restriction. SIRT1 activation during fasting not only relies on the increase in the NAD(+)/NAD ...

2011

Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling

Johan Auwerx, Hiroyasu Yamamoto

The formation of myelin by Schwann cells (SCs) occurs via a series of orchestrated molecular events. We previously used global expression profiling to examine peripheral nerve myelination and identified the NAD(+)-dependent deacetylase Sir-two-homolog 2 (S ...

2011