Carlotta Guiducci

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Novel Front-End Circuit Architectures for Integrated Bio-Electronic Interfaces

Alexandre Schmid, Carlotta Guiducci, Yusuf Leblebici

2008

Novel front-end circuit architectures for integrated bio-electronic interfaces

Alexandre Schmid, Carlotta Guiducci, Yusuf Leblebici

The prospective use of upcoming nanometer CMOS technology nodes (65nm, 45nm, and beyond) in bio-electronic interfaces is raising a number of important issues concerning circuit architectures and design. In particular, the advantages of scaling and higher d ...

2008

Innovative optoelectronic approaches to biomolecular analysis with arrays of silicon devices

Carlotta Guiducci

This paper intends to provide a brief survey of the most advanced implementations of molecular analysis tools based on microtechnologies and to discuss a new approach for the development of integrated molecular analysis. The technique presented hereafter c ...

2008

High Parallelism, Portability, and Broad Accessibility: Technologies for Genomics

Carlotta Guiducci

Biotechnology is an area of great innovations that promises to have deep impact on everyday life thanks to profound changes in biology, medicine, and health care. This article will span from the description of the biochemical principles of molecular biolog ...

2008

Real-Time High-Sensitivity Impedance Measurement Interface for Tethered BLM Biosensor Arrays

Giovanni De Micheli, Horst Vogel, Carlotta Guiducci, Samuel Terrettaz, Yusuf Leblebici, Luca Benini, Yüksel Temiz

This paper presents a switched-capacitor (SC) current integrator circuit for impedance measurement of tethered bilayer lipid membrane (tBLM) biosensors. The circuit comprises a small number of high performance components enabling enhanced experimental flex ...

2008

Real-time high-sensitivity impedance measurement interface for tethered BLM biosensor arrays

Giovanni De Micheli, Horst Vogel, Carlotta Guiducci, Samuel Terrettaz, Yusuf Leblebici, Luca Benini, Yüksel Temiz

2008

Electronic detection of DNA hybridization: Toward CMOS microarrays

Carlotta Guiducci

2007

A fully electronic label-free DNA sensor chip

Sandro Carrara, Carlotta Guiducci

This paper presents a microfabricated DNA chip for fully electronic, label-free DNA recognition, based on capacitance measurements. The chip has been fabricated in 0.5-mu m CMOS technology and it features an array of individually addressable sensing sites ...

2007

Interface Layering Phenomena in Capacitance Detection of DNA with Biochips

Giovanni De Micheli, Sandro Carrara, Carlotta Guiducci, Yusuf Leblebici, Luca Benini, Bruno Samori

Reliable DNA detection is of great importance for the development of the Lab-on-chip technology. The effort of the most recent projects on this field is to integrate all necessary operations, such as sample preparation (mixing, PCR amplification) together ...

2007

Fully Electronic CMOS DNA Detection Array Based on Capacitance Measurement with On-Chip Analog-to-Digital Conversion

Carlotta Guiducci, Giampaolo Zuccheri

An 8 times 16 array of sensing micro-sites employs a fully-electrical label-free technique for DNA recognition using capacitance measurement and is fabricated in 0.5mum CMOS with added noble metal. Repeatability and parallel detection capability have been ...

2006

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