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Thijs Pols

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Related publications (8)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue

Kristina Schoonjans, Alessia Perino, Vera Monica Lemos Da Silva, Mitsunori Nomura, Thijs Pols, Laura Alejandra Velazquez Villegas, Marika Olga Zietak

Nature Research2018

Probing the Binding Site of Bile Acids in TGR5

Johan Auwerx, Kristina Schoonjans, Thijs Pols

TGR5 is a G-protein-coupled receptor (GPCR) mediating cellular responses to bile acids (BAs). Although some efforts have been devoted to generate homology models of TGR5 and draw structure-activity relationships of BAs, none of these studies has hitherto d ...

American Chemical Society2013

TGR5 reduces macrophage migration through mTOR-induced C/EBP beta differential translation

Kristina Schoonjans, Alessia Perino, Matthias Alexander Sokrates Stein, Mitsunori Nomura, Thijs Pols

The bile acid-responsive G protein-coupled receptor TGR5 is involved in several metabolic processes, and recent studies suggest that TGR5 activation may promote pathways that are protective against diet-induced diabetes. Here, we investigated the role of m ...

American Society for Clinical Investigation2014