Person
Patrick Martin Seitz
This person is no longer with EPFL
Related publications (6)
Mechanistic aspects of DNA uptake in naturally competent Vibrio cholerae
The physiological state of competence for natural transformation allows bacteria to take up free DNA from the environment and recombine it into their genome. As one of three modes of horizontal gene transfer, natural transformation has hence contributed su ...
EPFL2014DNA Transport across the Outer and Inner Membranes of Naturally Transformable Vibrio cholerae Is Spatially but Not Temporally Coupled
Melanie Blokesch, Patrick Martin Seitz
The physiological state of natural competence for transformation allows certain bacteria to take up free DNA from the environment and to recombine such newly acquired DNA into their chromosomes. However, even though conserved components that are required t ...
American Society for Microbiology2014ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Vibrio cholerae Cells
Aleksandra Radenovic, Matteo Dal Peraro, Melanie Blokesch, Lorenz Jan Steinbock, Roman Bulushev, Patrick Martin Seitz, Hasan Pezeshgi Modarres
The DNA uptake of naturally competent bacteria has been attributed to the action of DNA uptake machineries resembling type IV pilus complexes. However, the protein(s) for pulling the DNA across the outer membrane of Gram-negative bacteria remain speculativ ...
Public Library Science2014DNA-uptake machinery of naturally competent Vibrio cholerae
Melanie Blokesch, Patrick Martin Seitz
Natural competence for transformation is a mode of horizontal gene transfer that is commonly used by bacteria to take up DNA from their environment. As part of this developmental program, so-called competence genes, which encode the components of a DNA-upt ...
National Academy of Sciences2013Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria
Melanie Blokesch, Patrick Martin Seitz
Bacterial genomics is flourishing, as whole-genome sequencing has become affordable, readily available, and rapid. As a result, it has become clear how frequently horizontal gene transfer (HGT) occurs in bacteria. The potential implications are highly sign ...
Wiley-Blackwell2013Quorum Sensing Contributes to Natural Transformation of Vibrio cholerae in a Species-Specific Manner
Melanie Blokesch, Patrick Martin Seitz, Gaia Francesca Marianne Suckow
Although it is a human pathogen, Vibrio cholerae is a regular member of aquatic habitats, such as coastal regions and estuaries. Within these environments, V. cholerae often takes advantage of the abundance of zooplankton and their chitinous molts as a nut ...
American Society for Microbiology2011