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Maaike Hélène Oosterveer

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Related publications (5)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Hepatic glucose sensing and integrative pathways in the liver

Kristina Schoonjans, Maaike Hélène Oosterveer

The hepatic glucose-sensing system is a functional network of enzymes and transcription factors that is critical for the maintenance of energy homeostasis and systemic glycemia. Here we review the recent literature on its components and metabolic actions. ...

Springer Basel Ag2014

Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease

Kristina Schoonjans, Pan Xu, Vera Monica Lemos Da Silva, Hadrien Charles Edouard Demagny, Dongryeol Ryu, Xu Wang, Matthias Alexander Sokrates Stein, Maaike Hélène Oosterveer

Hepatic steatosis is caused by metabolic imbalances that could be explained in part by an increase in de novo lipogenesis that results from increased sterol element binding protein 1 (SREBP-1) activity. The nuclear receptor liver receptor homolog 1 (LRH-1) ...

Amer Soc Clinical Investigation Inc2017

LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer

Johan Auwerx, Kristina Schoonjans, Arnaud Comment, Hadrien Charles Edouard Demagny, Dongryeol Ryu, Xu Wang, Emine Can, Norman Lionel Moullan, Pan Xu, Matthias Alexander Sokrates Stein

Various tumors develop addiction to glutamine to support uncontrolled cell proliferation. Here we identify the nuclear receptor liver receptor homolog 1 (LRH-1) as a key regulator in the process of hepatic tumorigenesis through the coordination of a noncan ...

Cold Spring Harbor Laboratory2016