Person

Elpida Tsika

Related publications (13)

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

Hilal Lashuel, Patrick Aebischer, Bernard Schneider, Niels Erik Lion, Elpida Tsika, Darren Moore, Michel Prudent, Bruno Claude Daniel Fauvet, Mohamed Bilal Fares, Philippe Guillaume Coune, Martial Mbefo Kamdem, Carole Desobry

Since the discovery and isolation of α-synuclein (α-syn) from human brains, it has been widely accepted that it exists as an intrinsically disordered monomeric protein. Two recent studies suggested that α-syn produced in Escherichia coli or isolated from m ...

2012

Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease

Elpida Tsika, Darren Moore, Alzbeta Trancikova

Mitochondria are highly dynamic, multifunctional organelles. Aside from their major role in energy metabolism, they are also crucial for many cellular processes including neurotransmission, synaptic maintenance, calcium homeostasis, cell death, and neurona ...

2012

Mechanisms of LRRK2-Mediated Neurodegeneration

Elpida Tsika, Darren Moore

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene represent the most common cause of familial Parkinson's disease (PD), whereas common variation at the LRRK2 locus is associated with an increased risk of idiopathic PD. Considerable progress has be ...

Current Science Inc., Springer2012

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