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Oliver Hantschel

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Publications by Oliver Hantschel | EPFL Graph Search

Oliver Hantschel

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Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly

Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K)

Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

Monobodies as enabling tools for structural and mechanistic biology

Targeted protein degradation through cytosolic delivery of monobody binders using bacterial toxins

Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

Selective Targeting of SH2 Domain–Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies

Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions