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Benjamin Samuel Murray

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Related publications (10)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation

Paul Joseph Dyson, Tina Riedel, Benjamin Samuel Murray

The 'acidic patch' is a highly electronegative cleft on the histone H2A-H2B dimer in the nucleosome. It is a fundamental motif for protein binding and chromatin dynamics, but the cellular impact of targeting this potentially therapeutic site with exogenous ...

Nature Research2017

An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode

Paul Joseph Dyson, Ursula Röthlisberger, Giulia Palermo, Thibaud Edouard Alistair von Erlach, Benjamin Samuel Murray

Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions. Many different intercalator compounds have been studied because of their activity as mutagens or drugs ...

Wiley-VCH Verlag GmbH2016

Recent progress in the development of organometallics for the treatment of cancer

Paul Joseph Dyson, Benjamin Samuel Murray

From their early successes in medicine, organometallic compounds continue to attract interest as potential chemotherapeutics to treat a range of diseases. Here, we show from recent literature selected largely from the last two years that organometallics of ...

2019