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Marlen Knobloch

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution

Matthias Lütolf, Sonja Giger, Marlen Knobloch, Mergim Ramosaj

Fatty acid beta-oxidation (FAO), the breakdown of lipids, is a metabolic pathway used by various stem cells. FAO levels are generally high during quiescence and downregulated with proliferation. The endogenous metabolite malonyl-CoA modulates lipid metabol ...

2020

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

Matthias Lütolf, Marlen Knobloch

Mechanisms controlling the proliferative activity of neural stem and progenitor cells (NSPCs) have a pivotal role to ensure life-long neurogenesis in the mammalian brain(1). How metabolic programs are coupled with NSPC activity remains unknown. Here we sho ...

Nature Publishing Group2013

Predicting stem cell fate changes by differential cell cycle progression patterns

Matthias Lütolf, Daniel Sage, Daniel Andreas Schmitter, Yuya Okawa, Marlen Knobloch

Stem cell self-renewal, commitment and reprogramming rely on a poorly understood coordination of cell cycle progression and execution of cell fate choices. Using existing experimental paradigms, it has not been possible to probe this relationship systemati ...

Company of Biologists2012