Publications by Fabiana Pereira Da Costa Fraga

p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats

Nikolaos Stergiopoulos, Fabiana Pereira Da Costa Fraga, Allancer Divino De Carvalho Nunes

Aims:Diminazene aceturate, a putative ACE2 activator, is susceptible to cleavage resulting in the formation of paminobenzamidine (PAB). This study aimed to investigate the effects of PAB in addressing cardiovascular dysfunctions in spontaneously hypertensi ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced by High-Fat Diet in an MMP-Dependent Mechanism

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rafaela Fernandes Da Silva, Augusto Martins Lima, Fabiana Pereira Da Costa Fraga, Maiia Bragina, Léa Liliane Colette Anguenot

Background: An increased fibrosis of the corpora cavernosa is a prevalent process that underlies most cases of erectile dysfunction. Apelin, an endogenous circulating peptide, has been documented as an important effector on cardiovascular homeostasis, cont ...

ELSEVIER SCI LTD2021

Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Maiia Bragina, Babak Ebadi Shirmard

Background: The renin-angiotensin system (RAS) plays an important role in erectile function. The RAS contains 2 major axes: one deleterious, composed of ACE-Ang II-AT1 receptor, and another protective, composed of ACE2-Ang-(1-7)-Mas receptor. While aging i ...

ELSEVIER SCI LTD2020

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Nikolaos Stergiopoulos, Olivier Burri, Marc Chambon, Rodrigo Araujo Fraga Da Silva, Fabiana Pereira Da Costa Fraga, Julien Bortoli Chapalay, Augusto Martins Lima, Maiia Bragina

Despite significant advances in the treatment of cardiovascular diseases, antiplatelet therapies are still associated with a high risk of hemorrhage. In order to develop new drugs, methods to measure platelet function must be adapted for the high-throughpu ...

TAYLOR & FRANCIS INC2019

Fabiana Pereira Da Costa Fraga

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p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced by High-Fat Diet in an MMP-Dependent Mechanism

Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Age-related changes in vascular responses to angiotensin-(1-7) in female mice

Apelin-13 treatment enhances the stability of atherosclerotic plaques

PROTECTIVE EFFECT OF APELIN-13 AGAINST HYPERCHOLESTEROLEMIA-INDUCED FIBROSIS OF THE CORPUS CAVERNOSUM

Ace-Ang Ii-At1 Axis Of Renin-Angiotensin System Is Associated With Aging-Related Penile Fibrosis

Apelin-13 treatment enhances the stability of atherosclerotic plaques

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced By Hypercholesterolemia

p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced by High-Fat Diet in an MMP-Dependent Mechanism

Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Age-related changes in vascular responses to angiotensin-(1-7) in female mice

Apelin-13 treatment enhances the stability of atherosclerotic plaques

PROTECTIVE EFFECT OF APELIN-13 AGAINST HYPERCHOLESTEROLEMIA-INDUCED FIBROSIS OF THE CORPUS CAVERNOSUM

Ace-Ang Ii-At1 Axis Of Renin-Angiotensin System Is Associated With Aging-Related Penile Fibrosis

Apelin-13 treatment enhances the stability of atherosclerotic plaques

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced By Hypercholesterolemia