Fabiana Pereira Da Costa Fraga

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Related publications (20)

Diminazene Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Injury

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

IntroductionAngiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin angiotensin system, which breaks down angiotensin II and forms angiotensin-(1-7). In erectile tissues, it has been documented that angiotensin II contributes to the development ...

Wiley-Blackwell2015

Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Maiia Bragina, Fabiana Pereira Da Costa Fraga

Angiotensin (Ang) II contributes to the development of atherosclerosis, while Ang-(1-7) has atheroprotective actions. Accordingly, angiotensin-converting enzyme 2 (ACE2), which breaks-down Aug 11 and forms Ang-(1-7), has been suggested as a target against ...

Elsevier2015

Diminazene Enhances Stable Phenotype Of Atherosclerotic Plaques

Nikolaos Stergiopoulos, Rodrigo Araujo Fraga Da Silva, Fabiana Pereira Da Costa Fraga

Elsevier Ireland Ltd2015

Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques

Nikolaos Stergiopoulos, Katia Galan, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Luciano Dos Santos Aggum Capettini

Angiotensin (Ang)-(1-7), acting through the receptor Mas, has athero-protective effects; however, its role on plaque vulnerability has been poorly studied. Here, we investigated the expression of the renin-angiotensin system (RAS) components in stable and ...

Schattauer2014

An Increased Arginase Activity Is Associated with Corpus Cavernosum Impairment Induced by Hypercholesterolemia

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Younouss Faye

IntroductionHypercholesterolemia is a prevalent risk factor for the development of erectile dysfunction (ED), mostly due to an increase in oxidative stress and impaired nitric oxide (NO) bioavailability within the penis. Arginase is an enzyme that shares t ...

Wiley-Blackwell2014

Ace2 Is Expressed In The Corpus Cavernosum And Produces Beneficial Effects Against Hypercholesterolemic-Induced Injures

Nikolaos Stergiopoulos, Rodrigo Araujo Fraga Da Silva, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

Wiley-Blackwell2014

Angiotensin-Converting Enzyme 2 Is Expressed In Corpus Cavernosum And Produces Beneficial Effects Against Hypercholesterolemia-Induced Injuries

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

Wiley-Blackwell2014

Arginase Inhibition Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Impairment

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

Wiley-Blackwell2014

An Oral Formulation of Angiotensin-(1-7) Reverses Corpus Cavernosum Damages Induced by Hypercholesterolemia

Nikolaos Stergiopoulos, Fabiana Pereira Da Costa Fraga, Danielle Gomes Passos Silva

Introduction The renin angiotensin system plays a crucial role in erectile function. It has been shown that elevated angiotensin-II levels contribute to the development of erectile dysfunction (ED). Oppositely, angiotensin-(1-7) (Ang-[1-7]) mediates penile ...

Wiley-Blackwell2013

ACE2 Activation Protects Corpus Cavernosum Impairment Induced by Hypercholesterolemia

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

Lippincott Williams & Wilkins2013

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Angiotensin-Converting Enzyme 2 Is Expressed In Corpus Cavernosum And Produces Beneficial Effects Against Hypercholesterolemia-Induced Injuries

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Fabiana Pereira Da Costa Fraga, Younouss Faye

Wiley-Blackwell2014