Publications by Simone Ellen Joze Duis

A brain-spine interface alleviating gait deficits after spinal cord injury in primates

Silvestro Micera, Grégoire Courtine, Quentin Barraud, Jocelyne Bloch, Tomislav Milekovic, Eduardo Martin Moraud, Marco Capogrosso, Elodie Rey, Fabien Bertrand Paul Wagner, Jérôme Gandar

Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer interfaces(1-3) have directly linked cortical activity to electrical stimulation of muscles, and have th ...

Nature Publishing Group2016

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Quentin Barraud, Jocelyne Bloch, Marco Capogrosso, Eduardo Martin Moraud, Pavel Musienko, Nikolaus Wenger, Natalia Pavlova

Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in animal models and humans. However, the physiological principles underlying the effect of this intervention remain poorly understood, which has limited the ther ...

Nature Publishing Group2016

Engagement of the Rat Hindlimb Motor Cortex across Natural Locomotor Behaviors

Silvestro Micera, Grégoire Courtine, Rubia van den Brand, Jacopo Rigosa, Julie Kreider, Lucia Florinda Friedli Wittler, Janine Beauparlant, Simone Ellen Joze Duis

Contrary to cats and primates, cortical contribution to hindlimb locomotor movements is not critical in rats. However, the importance of the motor cortex to regain locomotion after neurological disorders in rats suggests that cortical engagement in hindlim ...

Soc Neuroscience2016

Biomaterials. Electronic dura mater for long-term multimodal neural interfaces

Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Quentin Barraud, Léonie Asboth, Eduardo Martin Moraud, Tomislav Milekovic, Marco Capogrosso, Pavel Musienko, Nicolas Vachicouras

The mechanical mismatch between soft neural tissues and stiff neural implants hinders the long-term performance of implantable neuroprostheses. Here, we designed and fabricated soft neural implants with the shape and elasticity of dura mater, the protectiv ...

American Association for the Advancement of Science2015

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

Silvestro Micera, Grégoire Courtine, Eduardo Martin Moraud, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler, Simone Ellen Joze Duis, Isabel Laura Vollenweider, Kay Alexander Bartholdi

Half of human spinal cord injuries lead to chronic paralysis. Here, we introduce an electrochemical neuroprosthesis and a robotic postural interface designed to encourage supraspinally-mediated movements in rats with paralyzing lesions. Despite the interru ...

American Association for the Advancement of Science2012