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Alessandro Barducci

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Alessandro Barducci

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Data-driven large-scale genomic analysis reveals an intricate phylogenetic and functional landscape in J-domain proteins

Molecular dissection of amyloid disaggregation by human HSP70

Function, evolution, and structure of J-domain proteins

Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins

Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes

Molecular chaperones inject energy from ATP hydrolysis into the non-equilibrium stabilisation of native proteins

Modeling Hsp70/Hsp40 interaction by multi-scale molecular simulations and co-evolutionary sequence analysis

Effect of the Synaptic Plasma Membrane on the Stability of the Amyloid Precursor Protein Homodimer